Skin Mechanisms

Image Skin Mechanisms The search for further knowledge on skin functions and mechanisms is at the core of many biomedical and biopharmaceutical research programs today. The extension and complexity of the skin justifies its multiple roles, affecting all physiological processes, far beyond its “barrier” characteristics. More research on skin physiology is needed to better understand various disease mechanisms, and these need not be confined to the skin itself. Skin is also a target for new molecules, supplements, materials and even instruments, with the poten... Read More

Neurosciences

Image Neurosciences This Research Topic will cover the state of the art of animal model data collection, the development of new methods and tools for the analysis of animal models’ large data sets to produce high-quality atlases from population data, implementing translational studies, aiming to deepen our understanding of human psychiatric pathologies and diseases via their manifestation in different animal models We will welcome articles contributing to the construction and dissemination of animal model atlases; the dissemination, curation, and descrip... Read More

Biomarkers, Cytokines, and Chemokines

Image Biomarkers, Cytokines, and Chemokines Understanding the microenvironment within skin cancers is key for the development of new preventative and therapeutic treatment options. Research advances in skin cancers such as melanoma have revolutionized immunotherapeutic treatment options, for example through the provision of checkpoint inhibitor trials that have benefitted not just melanoma patients, but also patients with a wide array of other cancers, including less readily accessible cancer types. However, checkpoint inhibitor success is limited in melanoma and unlike... Read More

Artificial Intelligence in Dermatology

Image Artificial Intelligence in Dermatology The increasing presence of artificial intelligence (AI) worldwide, has led to numerous attempts at leveraging such technology for challenging healthcare problems. In the field of dermatology, the most progress thus far, has taken place in the field of melanoma diagnosis. Multiple original articles and several reviews have been published demonstrating that camera systems with algorithmic processing abilities may be able to differentiate between nevi and malignant lesions with similar accuracy to certified dermatologi... Read More

Non-Coding RNAs

Image Non-Coding RNAs Non-coding RNAs are critical molecules that constitute a substantial amount of the transcriptome. We have witnessed an ever-increasing repository of non-coding RNAs (ncRNAs) in the last decade, especially with the large scale application of high throughput sequencing technologies. These ncRNAs include, but are not limited to, miRNAs, siRNAs, long non-coding RNAs (lncRNAs), circular intronic RNAs (ciRNAs) and circular RNAs (circRNAs) originated from back-spliced exons. ncRNAs have been demonstrated to involved in all important biological processes a... Read More

Shaping Genes, Genomes, Populations and Species

Image Shaping Genes, Genomes, Populations and Species Plants have evolved an incredible diversity of strategies to optimize their sexual reproduction. The physical distance between plant male and female organs varies from hermaphroditism to biparental reproduction. The investment of resources in different sexes is also extremely diverse. For example, male gamete dispersal can be wholly aspecific, relying on the mass production of pollen to saturate the environment and maximize the chances to encounter the maximum of receptive females through wind dispersal. On the contr... Read More

3D Modelling of Mammalian Embryos and Organs

Image   During the past few years, mammalian development has been extended in vitro beyond the pre-implantation and post-implantation period. The exploitation of three dimensional (3D) culture systems has allowed to recapitulate gastrulation and, with the creation of organoids that summarize the process of organogenesis, to mimic the cellular organization and function of specific tissues and organs. The most recent advancements in computing science coupled with molecular technologies allowed a tremendous leap forward in our capacity to characterize the molecular networks ... Read More

Quantitative genetic studies Gene–environment and its significance

Image Quantitative genetic studies Gene–environment and its significance  Journal of Pharmacology and Therapeutic Research is an open access, peer reviewed journal that focuses on the interdisciplinary research offering therapeutic solutions to various neurological, genetics, psychological, and respiratory issues affecting the human beings. Gene–environment correlations (... Read More

Epigenetics & Mammalian Tissues

Image In Eva Jablonka and Lamb’s words, epigenetics is one of the four dimensions of evolution. After decades thinking and acting as if the genome determined the absolute fate of any life form in Earth, the relevance of epigenetics for mammalian life, disease and death is now recognized. In fact, assuming similar genomes, lifespan, life style, and risk of diseases, etc. results from a balance between genes and epigenetic traits. The Research Topic aims to show the differences of epigenetic traits between tissues, their physiological relevance and potential to target epigenetic mechanisms in... Read More

Advances in Genomics of Crossbred Farm Animals

Image Crossbreeding is a common strategy to enhance animal production because it can capitalize on breed complementary and heterosis. To date, crossbreeding has been a significant form of producing commercial animals in pigs and chickens. There are also composite animals, such as Brangus cattle, which combined “superior” characters of Angus and Brahman and retain some heterosis (hybrid vigor) in future generations without crossbreeding and maintained like purebred animals. In the past decades, advances in animal genomics have fundamentally revolutionized all the aspects of a... Read More

Journal of RNA and Genomics Accomplished 15 Years Milestone of Research Publication Journey: Thanks to Its Eminent Researchers

Image Journal of RNA and Genomics celebrates more than a decade of its existence in the field of Genomic research publishing and research for all the authors, researchers, editors and student to contribute their latest research findings as research, review, short commentary, case report articles i.e full length articles to this jour... Read More